The present study was undertaken to get further information on the migratory
} behavior of Taxocara cans larvae in the central nervous system in experimentally infected ´mice.
Mice were infected with approximately 500 of infective eggs of T. cans.. Actor-ding to the schedule, mice, 5 males and 5 females, were sacrificed at 2, 3, 5, 7, 14,
1 21, 28 and 56 days after infection and the brain tissue was extracted from each mouse and devided into six parts cerebrum, cerebellum, medulla oblongata, olfactory bulb, pituitary and spinal cord. Number of the larvae was counted qualitatively and quantitatively.
The results are summarized as follows
PP. 1. Total recovery rates (in average) of the larvae in the brain at the various intervals gradually increased from 0.4% to 10.6% with the highest rate on the 28th
cio. day of post-infection.
2. Total recovery rates (in average) of the larvae obtained throughout the study were 54.2% in male and 45.8% in female, out of 504 larvae.
3. Distribution rates of the larvae were revealed as high as 57.5% in cerebrum and 32.5 % in cerebellum, and 4.4 % in medulla oblongata, 2.8 % in spinal cord, 2.0 % in olfactory bulb and 1.6 % in pituitary in decreasing order.
4. Number of the larvae per mg. of wet weight of the brain found was 0.06 in cerebrum and cerebellum, 0.03 in olfactory bulb and pituitary, 0.02 in medulla oblongata and 0.01 in spinal cord, respectively.
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